Table 3.
Criterion | Definition |
---|---|
Age of patient at disease onset in years | Development of symptoms or findings related to Takayasu arteritis at age <40 years |
Claudication of extremities | Development and worsening of fatigue and discomfort in muscles of one or more extremity while in use, especially the upper extremities |
Decreased brachial artery pulse | Decreased pulsation of one or both brachial arteries |
Blood pressure difference >10 mmHg | Difference of >10 mmHg in systolic blood pressure between arms |
Bruit over subclavian arteries or aorta | Bruit audible on auscultation over one or both subclavian arteries or abdominal aorta |
Arteriogram abnormality | Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities, not due to arteriosclerosis, fibromuscular dysplasia, or similar causes; changes are usually focal or segmental |
Takayasu arteritis is classified if at least three of the six criteria are present. The presence of three or more criteria yields a sensitivity of 90.5% and a specificity of 97.8%