Table 1.
Clinical characteristics of the study population
| Characteristics | DMa (N = 225) |
CRIb (N = 196) |
P |
|---|---|---|---|
| Gender (M/F) | 76/149 | 65/131 | 0.89d |
| Age (years) | 60.6 ± 11.5 | 57 ± 12.8 | 0.10c |
| Duration of Diabetes (years) | 17.07 ± 6.69 | 10.4 ± 7.7 | <0.05c |
| Hb A1c (%) | 7.3 ± 1.0 | 7.5 ± 1.1 | 0.949c |
| Systolic pressure (mm Hg) * | 140 (106-190) | 150 (110-210) | 0.002e |
| Diastolic pressure (mm Hg) * | 84 (80-104) | 90 (70-110) | 0.025e |
| Serum creatinine (μmol/l) * | 84 (35-108) | 177 (124-1112) | <<0.05e |
| fUAER (mg/l) * | 10 (1-16) | 864 (320-1584) | <<0.05e |
| gGFR (mls/min/1.73 m2) | 81.44 ± 21.85 | 27.83 ± 24 | <<0.05c |
| Serum triglyceride (mmol/l) | 1.7 ± 0.67 | 1.8 ± 1.4 | 0.307c |
| Serum cholesterol (mmol/l) | 4.8 ± 0.97 | 4.9 ± 0.92 | 0.852c |
| Retinopathy (%) | 24 | 88 | |
| Non proliferative (%) | 15 | 35 | |
| Proliferative (%) | 8.6 | 53 | <<0.05d |
| Cardiovascular events (%) | 3 | 8.3 |
Data presented as mean ± SD (* median and range). atype 2 diabetes subjects without nephropathy (DM); bwith diabetic renal insufficiency (CRI); cStudent's t test; dPearson's χ2 test; eMann-Whitney U test, fUrinary albumin excretion rate, gGlomerular filtration rate.