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Responses of WT and Vmat2 HET mice in the forced-swim test. A, Effects of imipramine on immobility in forced swim of WT and HET mice. B, Imipramine effects on the latency to the first episode of immobility. C, Duration of first immobility bout after treatment with vehicle or imipramine. *p < 0.05 compared with WT mice treated with vehicle; #p < 0.05 for drug-treated mouse compared with the vehicle control from the same genotype; n = 7–11 mice/genotype.
