Table 2. Viable cells (concentration and percentage) of M. tuberculosis before and after competition assay between resistant and susceptible strains with the same genotype family.
Profile of susceptibility | Genotype | Strain | Before competition | After competition | Number of Generation (n) | |||
CFU/mL | % | CFU/mL | % | |||||
Test 1 | MDR | W-Beijing | 03-0265 | 3.86×104 | 9.5% | 5.2×105 | 0.5% | 3.8 |
S | W-Beijing | 02-2761 | 3.68×105 | 90.5% | 10.7×107 | 99.5% | 8.2 | |
Test 2 | MDR | Non-W-Beijing | 03-0850 | 2.23×104 | 7.0% | 5.2×107 | 82% | 11.2 |
S | Non-W-Beijing | 01-2522 | 2.97×105 | 93% | 1.11×107 | 18% | 5.2 | |
Test 3 | MDR | W-Beijing | 03-0265 | 3.86×104 | 63.38% | 6.60×106 | 1.57% | 7.4 |
MDR | Non-W-Beijing | 03-0850 | 2.23×104 | 36.32% | 4.13×108 | 98.43% | 14.2 | |
Test 4 | S | W-Beijing | 02-2761 | 3.68×105 | 55.34% | 1.11×109 | 98.82% | 11.6 |
S | Non-W-Beijing | 01-2522 | 2.97×105 | 44.66% | 1.32×107 | 1.17% | 5.5 |
S: susceptible to first and second-line drugs tested; MDR: multidrug resistant strain.