Figure 2.

(a) Overall structure of homotetrameric ZmPDC with triazole-ThDP (shown in stick representation) bound. The four protomers are shown in different colors. (b) View of ZmPDC rotated by 90° compared to the view in panel a. (c) Cartoon representation of one protomer of ZmPDC from panel a. The PYR domain (residues 1−188), R domain (residues 189−354), and PP domain (residues 355−566) are colored brown, yellow, and cyan, respectively. The termini of the peptide are labeled with N and C. The color scheme for stick representations in all figures is as follows: red for oxygen, blue for nitrogen, purple for magnesium, and orange for phosphate.