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Tempol reverses age-related collateral growth impairment. Diameter change of control and collateral vessels in tempol-pretreated aged rats after 7 days is expressed as percent change from day 0 (∗ p < 0.05 vs. same-animal control). The effect of tempol was completely inhibited by the eNOS inhibitor L-NAME (n = 3–5 rats/group).
