Table 3b. Exploratory Analysis Examining the Association of Major Haplotypes Formed by rs1880676, rs3810950, rs4838547, rs6537546, and rs1917810 with Three Nicotine Dependence Measures in the Replication Sample.
| Haplotype | Freq (%) | SQ | HSI | FTND |
|---|---|---|---|---|
| G-G-T-A-A | 34.7 | 2.351 (0.0187, 61) | 2.630 (0.00854, 63) | 2.589 (0.00962, 65) |
| G-G-G-A-G | 32.1 | −0.049 (0.961, 62) | −0.520 (0.603, 61) | −0.258 (0.797, 64) |
| G-G-A-T-A | 6.3 | 0.249 (0.803, 26) | 0.772 (0.440, 27) | 0.859 (0.390, 27) |
| A-A-G-A-G | 11.1 | −1.899 (0.0576, 43) | −1.913 (0.0557, 44) | −1.687 (0.0916, 45) |
| A-A-A-A-A | 13 | 0.186 (0.852, 49) | 0.301 (0.764, 49) | 0.108 (0.914, 52) |
| Global p-value | 7.804 (0.167) | 9.940 (0.0770) | 9.350 (0.0959) |
Three numbers within each cell are Z score, p-value, and informative family size (last two are in parentheses), respectively. Results for the dominant model are reported.