Table 3. A priori isolated regions of interest (based on literature review of frequently atrophied regions in MTLE), where the reduction of gray matter corresponded to standardized reduction in hippocampal fibers, as measured by the average MD. These results are corrected for multiple comparisons using FDR (the FDR corrected p-values marked with a star are statistically significant).
Structure | |||
---|---|---|---|
Ipsilateral to the side of HA | MD | ||
CC | p | FDR corrected | |
Amygdala | 0.542857 | 0.018261 | 0.0133* |
Anterior cingulum | 0.442857 | 0.049147 | 0.0333 |
Caudate | 0.489286 | 0.03208 | 0.03 |
Cerebelar hemisphere | 0.532143 | 0.020579 | 0.0200* |
Inferior temporal | 0.571429 | 0.013032 | 0.0067* |
Insula | 0.385714 | 0.077815 | 0.04 |
Middle cingulum | 0.492857 | 0.030976 | 0.0267 |
Middle temporal | 0.528571 | 0.021399 | 0.0233* |
Middle temporal pole | 0.535714 | 0.019783 | 0.0167* |
Pallidum | 0.546429 | 0.017533 | 0.0100* |
Parahippocampal | 0.382143 | 0.079912 | 0.0467 |
Posterior cingulum | 0.385714 | 0.077815 | 0.0433 |
Putamen | 0.592857 | 0.009923 | 0.0033* |
Superior temporal | 0.3 | 0.138658 | 0.05 |
Thalamus | 0.435714 | 0.052247 | 0.0367 |