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Properties of CD4 T-cell differentiation stages
| Functional characteristics | Naïve | Effector | Memory | Secondary effector |
|---|---|---|---|---|
| Effector function | – | ++++ | +++ | +++++ |
| IL-2:IL-10 ratio | +++ | + | +++++ | ++++ |
| AICD | – | ++++ | ++ | ? |
| Adhesion | – | ++++ | ++ | +++++ |
| Migration | Lymphoid | Non-lymphoid | Lymphoid | Non-lymphoid |
AICD, activation induced cell death; IL, interleukin.
