Table 1.
Characteristics of patients whose cells were used in flow cytometry analysis to establish regulatory T-cell frequencies
Characteristics of patients (PG1) whose cells were used for CD25 and Foxp3 expression (n= 55) | Characteristics of patients (PG2) whose cells were used for serial Foxp3 expression (n= 21) | |
---|---|---|
Median age | 59·5 years (22–82) | 63 years (25–81) |
Median creatinine | 113 μmol/l (65–947) | 211 μmol/l (78–657) |
Active disease | 17 | 21 |
Remission | 38 | 0 |
ANCA+ at sampling | 35 | 17 |
ANCA− at sampling | 20 | 4 |
Sampled at new presentation of disease | 10 | 17 |
Median time since diagnosis of disease to sampling | 142 weeks (0–1158) | 43 weeks (24–165) for four relapsed patients 0 weeks for patients with new diagnosis |
Median follow-up | 335 weeks (20–1200) | |
Death during follow-up | 6 | 0 |
ANCA, anti-neutrophil cytoplasm antibody.