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Relevant reaction pathways. a Reaction of 4-APC and hexanal (blue) through a transient imine. b Reaction of 4-APEBA and hexanal (blue) through a transient imine. c Reaction of 4-APEBA with hexanoic acid (green) through a transient O-acyl-isourea. In reaction C, the R and R1 groups arbitrarily represent the two peripheral groups of EDC
