rQT3 increased inhibition of tumor growth and prolonged survival. A, mice bearing small (left) or large (right) sporadic MPNST (STS26T) xenografts were treated with multiple i.t. doses of saline, G207, rQLuc, or rQT3 (arrows, 3 × 106 pfu/dose) and followed for tumor growth. B, NF-1–associated MPNST (S462.TY) xenografts were treated with saline or oHSV at 3 × 106 pfu/dose and followed for tumor growth (left) and survival (right). C, neuroblastoma (LA-N-5) xenografts were treated with saline or oHSV at 3 × 106 pfu/dose and followed for tumor growth. D, mice bearing dsRed-labeled MPNST (STS26T) xenografts were treated with oHSV as in A and imaged for in vivo tumor burden by ds-Red fluorescence at day 41.