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Representative FVIII:C vs. time curves from two adult patients as evaluated by one- or two-phase linear regression. When the full sampling schedule is used, the fitted curve is monophasic for patient A and biphasic for patient B. With data from the reduced sampling schedule, only monophasic curves can be fitted for both patients. Key to symbols: open and filled circles and dashed line = biphasic fit, filled circles and solid lines = monophasic fit.
