Figure 5.

Across trait and across studies correlations: (a) saline-induced locomotor activity: in our study two laboratories, Memphis (Cocaine) and UTHSC (Ethanol), collected data on open field locomotion following saline in 15 and 20 min on 64 BXD RI strains, respectively. We compared these data with data collected on saline-induced locomotor response by Demarest et al. (1999) on 25 BXD RI strains. Results indicate that there is good correlation among data on saline-induced locomotor response across the laboratories and to a previously published study. Correlations among the r_{Memphis,UTHSC} = 0.556,r_{Memphis,Demarest} = 0.781 and r_{Demarest,UTHSC} = 0.695. (b) Thermal nociception: thermal nociception (hot plate latency) was preformed in two laboratories, namely, ORNL and Memphis in this study. Data collected in this study were compared with a previously published study of thermal nociception by Mogil et al. (1997) and Brigman et al. (2009). Correlations ranged from 0.274 to 0.799 (Fig. 4b). The low correlation among the data collected at the Memphis and ORNL laboratories may be attributed to the two different hot plate temperatures used.