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. Author manuscript; available in PMC: 2010 Apr 19.
Published in final edited form as: Expert Opin Biol Ther. 2008 Jul;8(7):969–978. doi: 10.1517/14712598.8.7.969

Figure 2.

Figure 2

Cortex (a, b & c) and dentate gyrus (d, e & f) of Type 1 (a & d), Type 2 (b & e), and Type 3 (c & f) FTLD-U according to Sampathu & Cairns [1]. Type 1. Predominance of dystrophic neurites (DN) (a, inset) in cortex with round neuronal cytoplasmic inclusions (NCI) (d, inset) in the dentate gyrus. Type 2. Predominance of NCI, including granular cytoplasmic TDP-43 immunoreactivity, with sparse DN in cortex (b, inset) and dentate gyrus (e, inset). Type 3. NCI, DN & neuronal intranuclear inclusions (NII) (c, inset) and NCI and NII in dentate gyrus (f, inset).