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. 2010 Mar 30;102(8):1201–1206. doi: 10.1038/sj.bjc.6605620

Table 4. Sensitivity, specificity, PPV, and NPV for DEFAB cut-offs of ⩾3 and ⩾5.

  DEFAB score ⩾3, estimate (95% CI) DEFAB score ⩾5, estimate (95% CI)
Sensitivity 81.9% (74.7–87.7%) 67.8% (59.6–75.2%)
Specificity 50.1% (48.2–51.9%) 74.1 (72.5–75.7%)
ROC area 0.660 (0.627–0.692) 0.710 (0.671–0.748)
PPV 7.78% (6.50–9.21%) 11.9% (9.77–14.2%)
NPV 98.2% (97.4–98.8%) 97.8% (97.1–98.4%)

Abbreviations: CI=confidence interval; NPV=negative predictive value; PPV=positive predictive value; ROC=receiver operating characteristic curve.