Table 2. Treatment-related toxicities.

	Megestrol acetate					Metronomic cyclophosphamide
Grade	1	2	3	4	5	1	2	3	4	5
Fatigue	2	0	0	0	0	1	1	0	0	0
Hot flashes	1	0	0	0	0	0	0	0	0	0
Nausea	0	0	0	0	0	1	1	0	0	0
Vomiting	0	0	0	0	0	1	0	2	0	0
Anorexia	0	0	0	0	0	1	0	0	0	0
Compulsive eating	1	0	0	0	0	0	0	0	0	0
Hyper-triglyceridemia	0	0	1	0	0	0	0	0	0	0
Epigastralgia	0	0	0	0	0	1	0	0	0	0
Diarrhoea	0	1	0	0	0	0	0	0	0	0
Aphtosis	0	0	0	0	0	1	0	0	0	0
Anaemia	0	0	0	0	0	3	0	0	0	0
Neutropaenia	0	0	0	0	0	1	0	0	0	0
Phlebitis	0	1	0	0	1	0	0	0	0	0
Gynecomastia	1	0	0	0	0	0	0	0	0	0
Galactorrhoea	0	0	1	0	0	0	0	0	0	0
Libido alteration	0	1	0	0	0	0	0	0	0	0
Dysuria	0	0	0	0	0	0	1	0	0	0
Interstitial pneumonia	0	0	0	0	0	0	1	0	0	0
Oedema	1	2	0	0	0	0	0	0	0	0
Total	5	5	2	0	1	10	4	2	0	0