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. 2010 Mar 30;102(8):1244–1253. doi: 10.1038/sj.bjc.6605634

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Copyright © 2010 Cancer Research UK

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The effect of let-7f on KLK10 protein and mRNA expression in the OVCAR-3 cell line. (A) KLK10 protein expression was significantly decreased in cells transfected with let-7f (P<0.01). Protein expression was partially restored when cells were co-transfected with let-7f and its inhibitor anti-let-7f. There was a slight decrease in KLK10 protein expression when cells were transfected with a random sequence miR and miR-17. (B) There was a slight decrease in OVCAR-3 KLK10 mRNA expression when compared with cells transfected with either let-7f, let-7f and anti-let-7f, random sequence miR, or miR-17. ^*, P<0.01.