Figure 6.
The Vδ1 chain on γδ T cells of CMV-infected newborns preferentially pairs with a public Vγ8 chain. (A) The percentage of Vδ1+ γδ T cells positive for Vγ2/3/4, Vγ5/3, Vγ8, or Vγ9 determined in three CMV-infected (Pos4, Pos6, and Pos13) and three CMV-uninfected newborns. (B) Spectratyping for CDR3γ8 of six CMV-uninfected newborns (top row) and six CMV-infected newborns (bottom row). The arrow indicates the public CDR3γ8 sequence CATWDTTGWFKIF of 11 aa (Table S3). The CDR3γ8 of Pos13 contains 1 aa more (Y).