Table 1.
Patient characteristics at day of pharmacokinetic sampling
| Parameter | Median | Range |
|---|---|---|
| Age (years) | 56 | 45–59 |
| Plasma HIV-1 RNA (copies ml−1) | <40 | <40–58 |
| CD4+ lymphocytes (cells µl−1) | 210 | 81–270 |
| CD8+ lymphocytes (cells µl−1) | 1170 | 510–2120 |
| ASAT (U l−1) | 24 | 11–40 |
| ALAT (U l−1) | 39 | 16–83 |
| AP (U l−1) | 98 | 78–131 |
| GGT (U l−1) | 53 | 41–107 |
| Total bilirubin (µmol l−1) | 12 | 8–14 |
| Serum creatinine (µmol l−1) | 82 | 46–98 |
| Number of different antiretroviral drugs in antiretroviral treatment history | ||
| Nucleoside/nucleotide reverse transcriptase inhibitors | 6 | 5–7 |
| Protease inhibitors | 3 | 2–6 |
| Non-nucleoside reverse transcriptase inhibitors | 1 | 0–1 |
ALAT, alanine aminotransferase; AP, alkaline phosphatase; ASAT, aspartate aminotransferase; GGT, gamma-glutamyltransferase.