Table 2.

Observed pharmacokinetics in plasma and PBMCs

	Raltegravir	Etravirine		Darunavir		Ritonavir
Mean ± SD	Plasma	Plasma	PBMCs	Plasma	PBMCs	Plasma	PBMCs
n	11	9		10		10
Cpre-dose (mg l−1)	0.0690 ± 0.0507	0.235 ± 0.092	4.53 ± 6.01	1.89 ± 1.27	1.45 ± 1.11	0.124 ± 0.0741	0.976 ± 0.485
Cmax (mg l−1)	0.709 ± 0.760	0.444 ± 0.135	9.40 ± 6.47	4.47 ± 1.82	9.73 ± 5.37	0.350 ± 0.213	2.55 ± 1.22
tmax (h)	3.08 ± 2.47	2.89 ± 0.735	2.64 ± 0.907	2.23 ± 0.934	2.26 ± 1.31	3.42 ± 1.66	2.74 ± 2.29