Table 8.

Total melphalan concentrations and fu in each of the specifically-timed plasma samples collected from each patient. Data are mean ± standard deviation (SD)

Sample number	Time after infusion start (h)	Total melphalan concentration (µg ml−1)	fu
1	0.78 ± 0.27	7.85 ± 2.56	0.24 ± 0.08
2	0.90 ± 0.27	6.10 ± 1.93	0.24 ± 0.08
3	1.10 ± 0.27	4.62 ± 1.56	0.23 ± 0.09
4	1.26 ± 0.27	3.88 ± 1.37	0.24 ± 0.09
5	1.79 ± 0.29	2.45 ± 0.94	0.24 ± 0.09
6	2.87 ± 0.38	1.16 ± 0.60	0.24 ± 0.10
Significance*			NS DF = 5585, F = 0.23

^*Significance tested using one-way anova, Bonferroni test for multiple comparisons. NS, Not significant.