Figure 8. Network motif involving the putative antiviral transcription factor ALX1.
(A) The ALX1 gene is activated by IRF7. (B) ALX1 activates other genes such as PLA1A. The solid lines (A,B) represent EMSA-validated network connections. The dashed lines, completing a feed-forward loop (C) and indicating auto-regulation (D), were predicted computationally.