Table 3.
Effect of N- and C-terminal extensions with/without truncations on the procapsid structure and function*
Procapsid mutant |
Procapsid morphology |
DNA packaging |
Virion assembly |
---|---|---|---|
N-Ex | Normal | ↓ 10-fold | ↓ 100-fold |
C-Ex | Normal | ↓ 10-fold | ↓ 10-fold |
N-DeEx | Normal | ~0 | ~0 |
C-DeEx | Normal | ↓ 100-fold | ~0 |
The DNA packaging activity and phage assembly activity were given relative to those of the wild-type procapsid.