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. Author manuscript; available in PMC: 2011 Mar 19.
Published in final edited form as: Circ Res. 2010 Jan 21;106(5):880–890. doi: 10.1161/CIRCRESAHA.109.213256

Figure 4. Subcellular localization of Myozap within isolated cardiomyocytes and in the intact heart.

Figure 4

(A) Cardiomyocytes from adult mouse heart stained with a Myozap-specific antiserum reveal an intense signal at the intercalated disc, as shown by co-localization with cadherin. Also, a weak staining of the Z-discs is observed. Scalebar: 20 µm. (B) Sections of mouse heart showing a strong signal at the intercalated disc with Myozap antiserum, co-localizing with cadherin, plakoglobin as well as plakophilin-2. Scalebars: 20 µm. (C) Immunoelectron microscopy of a cryosection through a bovine heart utilizing the Myozap-antiserum. An intense signal is seen at the intercalated disc. Scalebar: 1.18 µm