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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Asian Nat Prod Res. 2010 Mar;12(3):227–232. doi: 10.1080/10286021003591617

Table 2.

Relative ratioa of EBV-EA activation with respect to positive control in presence of dehydrozingerone analogs and related compounds.

Compound Percentage EBV-EA positive cells
IC50
Compound concentration (mol ratio/TPAb)
1000 500 100 10
Dehydrozingerone (1)c 0±0.5 (70)d 44.2±1.9 75.5±2.6 95.4±0.2 372
16 0±0.2 (60) 19.0±1.3 65.2±2.0 88.7±0.4 216
17 0±0.4 (60) 21.9±1.5 67.8±2.1 90.0±0.2 234
18 0±0.3 (60) 20.7±1.5 66.9±2.1 89.3±0.3 220
19 0±0.4 (60) 23.5±1.5 71.0±2.3 95.1±0.1 242
20 0±0.4 (60) 24.9±1.3 73.9±2.3 97.7±0.2 250
21 0±0.4 (60) 22.8±1.3 70.9±2.0 93.7±0.3 239
22 0±0.6 (60) 38.5±1.7 72.0±2.3 92.1±0.2 368
23 0±0.2 (60) 21.5±1.2 68.9±2.1 91.7±0.3 238
24 0±0.3 (60) 20.1±1.3 66.2±2.0 89.0±0.3 220
Isoeugenol (3)c 16.7±1.5 (70) 53.5±1.9 81.0±2.7 100±0.1 490
25 0±0.2 (60) 19.9±1.1 66.0±1.9 89.5±0.4 219
26 0±0.4 (60) 22.8±1.4 68.0±2.2 92.7±0.2 236
27 0±0.3 (60) 21.8±1.3 67.3±2.1 90.3±0.3 234
28 NAe -
29 0±0.5 (60) 26.3±1.4 75.3±2.3 98.8±0.1 261
30 0±0.4 (60) 23.6±1.5 72.0±2.3 95.6±0.2 246
31 NA -
32 0±0.4 (60) 22.7±1.3 69.3±2.3 92.8±0.1 240
33 0±0.4 (60) 21.2±1.4 67.3±2.1 91.5±0.2 237

34 0±0.2 (60) 19.1±1.1 64.8±2.0 88.0±0.4 222
35 0±0.2 (60) 18.0±1.0 63.2±2.0 86.8±0.3 207
36 0±0.2 (60) 19.7±1.1. 63.2±2.0 86.8±0.3 219
37 0±0.2 (60) 22.8±1.3 67.7±2.1 90.5±0.3 231

Curcumin (2)c 0±0.4 (60) 21.1±1.1 80.1±2.4 100±0.1 379
38 0±0.2 (60) 19.6±1.1 76.5±2.4 98.5±0.1 253
39 0±0.1 (60) 17.3±0.9 72.6±2.1 92.4±0.3 240
a

Values represent percentages relative to the positive control value (100%).

b

TPA concentration is 20 ng/mL (32 pmol/mL).

c

Positive control

d

Values in parentheses are viability percentages of Raji cells.

e

Not applicable