Table 2.
Compound | Percentage EBV-EA positive cells |
IC50 | |||
---|---|---|---|---|---|
Compound concentration (mol ratio/TPAb) | |||||
1000 | 500 | 100 | 10 | ||
Dehydrozingerone (1)c | 0±0.5 (70)d | 44.2±1.9 | 75.5±2.6 | 95.4±0.2 | 372 |
16 | 0±0.2 (60) | 19.0±1.3 | 65.2±2.0 | 88.7±0.4 | 216 |
17 | 0±0.4 (60) | 21.9±1.5 | 67.8±2.1 | 90.0±0.2 | 234 |
18 | 0±0.3 (60) | 20.7±1.5 | 66.9±2.1 | 89.3±0.3 | 220 |
19 | 0±0.4 (60) | 23.5±1.5 | 71.0±2.3 | 95.1±0.1 | 242 |
20 | 0±0.4 (60) | 24.9±1.3 | 73.9±2.3 | 97.7±0.2 | 250 |
21 | 0±0.4 (60) | 22.8±1.3 | 70.9±2.0 | 93.7±0.3 | 239 |
22 | 0±0.6 (60) | 38.5±1.7 | 72.0±2.3 | 92.1±0.2 | 368 |
23 | 0±0.2 (60) | 21.5±1.2 | 68.9±2.1 | 91.7±0.3 | 238 |
24 | 0±0.3 (60) | 20.1±1.3 | 66.2±2.0 | 89.0±0.3 | 220 |
Isoeugenol (3)c | 16.7±1.5 (70) | 53.5±1.9 | 81.0±2.7 | 100±0.1 | 490 |
25 | 0±0.2 (60) | 19.9±1.1 | 66.0±1.9 | 89.5±0.4 | 219 |
26 | 0±0.4 (60) | 22.8±1.4 | 68.0±2.2 | 92.7±0.2 | 236 |
27 | 0±0.3 (60) | 21.8±1.3 | 67.3±2.1 | 90.3±0.3 | 234 |
28 | NAe | - | |||
29 | 0±0.5 (60) | 26.3±1.4 | 75.3±2.3 | 98.8±0.1 | 261 |
30 | 0±0.4 (60) | 23.6±1.5 | 72.0±2.3 | 95.6±0.2 | 246 |
31 | NA | - | |||
32 | 0±0.4 (60) | 22.7±1.3 | 69.3±2.3 | 92.8±0.1 | 240 |
33 | 0±0.4 (60) | 21.2±1.4 | 67.3±2.1 | 91.5±0.2 | 237 |
34 | 0±0.2 (60) | 19.1±1.1 | 64.8±2.0 | 88.0±0.4 | 222 |
35 | 0±0.2 (60) | 18.0±1.0 | 63.2±2.0 | 86.8±0.3 | 207 |
36 | 0±0.2 (60) | 19.7±1.1. | 63.2±2.0 | 86.8±0.3 | 219 |
37 | 0±0.2 (60) | 22.8±1.3 | 67.7±2.1 | 90.5±0.3 | 231 |
Curcumin (2)c | 0±0.4 (60) | 21.1±1.1 | 80.1±2.4 | 100±0.1 | 379 |
38 | 0±0.2 (60) | 19.6±1.1 | 76.5±2.4 | 98.5±0.1 | 253 |
39 | 0±0.1 (60) | 17.3±0.9 | 72.6±2.1 | 92.4±0.3 | 240 |
Values represent percentages relative to the positive control value (100%).
TPA concentration is 20 ng/mL (32 pmol/mL).
Positive control
Values in parentheses are viability percentages of Raji cells.
Not applicable