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(a) Density of filaments along protrusion leading edge is shown as a function of G-actin concentration. Leading-edge filaments are defined as those close to the membrane (with distance no larger than 2.7 nm, the effective size of one monomeric actin). (b) The ratio of the nucleation rate to the protrusion speed (i.e., the density of new filaments) is shown. The curve indicates that new filament density decreases with actin concentration.
