Table 1.

Parameters used in set of case studies reported in Fig. 2

Parameters	${\mathrm{P}}_{\mathrm{Cl}}^{\mathrm{bl}}$ = 0	${\mathrm{P}}_{\mathrm{Cl}}^{\mathrm{bl}}$ × 2	${\mathrm{G}}_{\mathrm{K}}^{\text{bl}}$ = 0	${\mathrm{G}}_{\mathrm{K}}^{\text{bl}}$ × 2	Reference	Concentrations (mM)
${\mathrm{G}}_{\mathrm{K}}^{\mathrm{o}}$, S/m2	10	10	0	21	10	Na+	20
${\mathrm{P}}_{\mathrm{K}}^{\text{bl}}$, μ m/s	8.0 e−2	8.0 e−2	10.5 e−2	5. e−2	8.0 e−2	K+	140
${\mathrm{P}}_{\mathrm{Cl}}^{\mathrm{bl}}$, μ m/s	0	1 e−1	5.2 e−2	5.2 e−2	5.2 e−2	Cl−	55
Jmax, mol/(m2s)						H+	4.2 e−5
NaK pump	1.33 e−5	1.75 e−5	1.6 e−5	1.6 e−5	1.6 e−5	${\text{HCO}}_3^{-}$	13
NKCC	1.25 e−5	1.5 e−5	1.25 e−5	1.25 e−5	1.25 e−5
NHE	4.5 e−6	4.5 e−6	4.5 e−6	4.5 e−6	4.5 e−6
AE	1.22 e−5	1.24 e−5	1.24 e−5	1.24 e−5	1.24 e−5
NBC	1.1 e−6	1.1 e−6	1.1 e−6	1.1 e−6	1.1 e−6

Reference values are the set of parameters that best reproduce the experimental data. Numbers in bold bring attention to values that differ from those for the reference case. Modifications in J_max were necessary to make all compared cases correspond to equivalent basal conditions. Values in the last column are the initial conditions for intracellular concentrations.