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. 2010 Jan 26;285(14):10583–10590. doi: 10.1074/jbc.M109.078006

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FIGURE 4. — ApoB-antisense LNA oligonucleotide reduces plasma triglycerides and cholesterol. Plasma triglycerides (A), cholesterol (B), and free fatty acids (C) were determined in C57Bl/6 mice 4 days after an intraperitoneal injection of apoB-antisense LNA oligonucleotide (filled bars) or saline (open bars). Mice were fasted for 12 h or allowed free access to chow prior to collecting blood for plasma analyses in the morning. Values are means ± S.E. The numbers of mice in each group are shown in the figure. ***, p < 0.0001.