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Expression of S100A8 and S100A9 in WT and UG-KO mice and expression of RAGE in B16F10 cells. S100A8 and S100A9 mRNA levels are dramatically elevated in the lungs of UG-KO mice compared with those of the WT littermates (A). The S100A8 and S100A9 protein levels were also significantly higher in the lung tissues (B) as well as in the serum (C) of the UG-KO mice compared with those of the WT littermates.
