TABLE 1.

Summary of C. elegans transcripts showing greater than 2-fold change in expression during Y. pestis infection

Group	Gene	Fold-changea	p valueb	Group	Gene	Fold-changea	p valueb
CUB-like domain	F35E12.5	62.54	0.0062	Proteolysis/hydrolysis	W03G1.7	13.55	0.0111
	C32H11.10	12.43	0.0355		F53A9.1	9.37	0.0195
	C32H11.12	9.97	0.0217		C05C10.4	5.48	0.0457
	F55G11.5	6.82	0.0178		K10C2.3	5.12	0.0189
	C32H11.4	6.52	0.0217		F21F8.4	4.45	0.0470
	F35E12.6	6.25	0.0217		K11D2.2	3.36	0.0264
	F08G5.6	6.21	0.0195		T10H4.12	2.57	0.0314
	C17H12.8	4.94	0.032		F55F3.2	2.20	0.0195
	F55G11.8	4.68	0.0219		F54F11.2	2.18	0.0256
	K08D8.5	3.59	0.0256		F27E5.1	2.10	0.0195
	ZK896.5	2.57	0.0149		Y16B4A.2	2.09	0.0460
	H20E11.1	2.03	0.0298		C55B7.3	−2.48	0.0249
	K10D11.5	2.00	0.0441	Lipid metabolism	F54F3.3	11.53	0.0173
	T05E12.6	−4.52	0.0217		Y65B4BR.1	10.01	0.0249
Sugar binding	F56D6.15	10.09	0.0173		K03H6.2	8.91	0.0062
	F56D6.2	9.24	0.0233		B0035.13	5.97	0.0227
	ZK666.6	6.88	0.0438		F09C8.1	4.95	0.0382
	F35C5.5	3.77	0.0282		F28H7.3	3.31	0.0217
	F35C5.9	3.59	0.0256		W06D12.3	−4.66	0.0216
	F40F4.6	3.42	0.0283	Metabolic Process	F41E6.5	4.71	0.0460
	Y54G2A.14	2.79	0.0282		T25B9.7	2.03	0.0256
	F38A5.3	2.74	0.0322		D1054.8	−2.55	0.0460
	Y54G2A.8	2.58	0.0329		C17C3.12	−3.33	0.0139
	F21H7.4	2.47	0.0329		F47C10.6	−3.83	0.0305
	F35C5.8	2.00	0.0329		C30G12.2	−4.08	0.0382
	T09F5.9	−4.19	0.0460		C04F5.7	−4.33	0.0322
Neuropeptide-like	F45E4.8	7.78	0.0327		C55B7.4	−8.32	0.0441
	Y45F10A.5	2.63	0.0295	Transport	K09C8.1	4.26	0.0178
	F37A8.4	2.58	0.0364		C18H9.5	−2.41	0.0012
	M01D7.5	2.54	0.0371		C35A5.3	−4.12	0.0219
	T23E7.4	2.26	0.0233		T10H9.5	−5.40	0.0280

^a Fold change represents the ratio of expression in C. elegans exposed to Y. pestis relative to expression on E. coli. Average expression levels from three samples were used to calculate fold change.

^b p values represent the corrected p value for multiple comparisons using the Benjamini-Hochberg method with a cutoff of 0.05.