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. 2010 Jan 24;285(14):10880–10889. doi: 10.1074/jbc.M109.081489

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FIGURE 6. — Excess lipids are stored in the liver of Sgpl1^−/− mice. Paraffin-embedded liver sections from (A) Sgpl1^+/+ or (B) Sgpl1^−/− mice were stained with H&E (×10 magnification). Frozen sections of liver from (C) Sgpl1^+/+ or (D) Sgpl1^−/− mice were stained with Oil red O (×40 magnification). Arrows indicate lipid deposits. Liver samples from (E) Sgpl1^+/+ or (F) Sgpl1^−/− mice were analyzed by electron microscopy (×6000 magnification). Arrowheads indicate examples of lipid droplets. Liver sections from (G) Sgpl1^+/+ or (H) Sgpl1^−/− mice immunostained with LAMP-2 antibody (brown reaction product) and counterstained with hematoxylin (×100 magnification).