TABLE 2.

Total SL levels in WT and CerS2 null mouse liver

The data are the sum of the individual SL species shown in Table 1 and supplemental Tables 1 and 2. With the exception of ceramide on day 7, SM on day 120, and HexCer on days 7 and 14 (p < 0.05), total ceramide, SM, and HexCer levels between WT and CerS2 null mice were statistically indistinguishable.

Age	Ceramide		SM		HexCer
	WT	CerS2 null	WT	CerS2 null	WT	CerS2 null
days	pmol/mg tissue
0	282 ± 49	203 ± 47	1153 ± 238	1402 ± 510	54.0 ± 5.6	52.8 ± 9.4
7	220 ± 30	114 ± 7	979 ± 215	707 ± 29	75.1 ± 3.5	48.0 ± 6.0
14	104 ± 0	121 ± 18	707 ± 109	827 ± 47	86.0 ± 11.1	50.1 ± 1.3
21	152 ± 12	117 ± 41	920 ± 16	1253 ± 304	99.3 ± 20.2	57.2 ± 15.7
30	171 ± 70	149 ± 4	859 ± 302	887 ± 42	40.1 ± 23.3	29.6 ± 1.6
60	175 ± 99	264 ± 199	780 ± 280	1093 ± 423	37.5 ± 19.5	48.9 ± 25.9
120	193 ± 23	247 ± 15	559 ± 62	1180 ± 69	19.1 ± 6.8	49.1 ± 15.7