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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Behav Neurosci. 2010 Apr;124(2):204–210. doi: 10.1037/a0018909

Figure 2.

Figure 2

Effects of post-session prazosin injections on extinction of cocaine-induced conditioned place preference. (A) Percent time spent on the cocaine-paired floor is shown for the eight sessions of extinction and for the two test sessions following post-extinction reconditioning (RC) with 5 mg/kg (RC5) or 20 mg/kg (RC20) of cocaine. Each of the extinction sessions was followed by IP injection of 1.0 mg/kg prazosin (n=15), 3.0 mg/kg prazosin (n=16), or vehicle (n=16). Mean time spent on the GRID floor during (B) the first and last extinction session and (C) the two sessions following reconditioning is shown for mice that received cocaine pairings with the GRID floor (G+) and mice that received pairings with the HOLE floor (G−). Error bars represent standard error of the mean.