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Profile of Pulse, Mean Arterial pressure, Cardiac Output and Systemic Vascular Resistance in control and acetaminophen injured pigs. Chart A demonstrates a progressive increase in pulse and concomitant reduction in MAP following liver injury. Furthermore, chart B demonstrates a marked increase in cardiac output (CO) and decreased systemic vascular resistance (SVR) following liver injury. These haemodynamic changes are in keeping with the multi-organ failure seen in acute liver injury.
