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. 2010 Mar 30;10:34. doi: 10.1186/1471-230X-10-34

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Copyright ©2010 Newsome et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histology. This figure depicts representative photographs of liver and renal sections. Panel a, represents liver tissue taken from a control pig. Panel b represents liver tissue taken from pig 4 and demonstrates moderate injury. There is diffuse microvesicular change, with moderately severe centrilobular necrosis. Panels c and d (higher power) represents liver tissue taken from pig 7 demonstrating more severe coagulative centrilobular necrosis. Panel e represents renal tissue taken from a control pig. Panel f represents liver tissue taken from pig 7 demonstrating severe vacuolar injury to the cortical tubules in keeping with the development of acute tubular necrosis.