Table 5.
First event model of the recurrent MI events in the LIPID study
| Risk factor | Hazard ratio | 95% CI | P-value |
|---|---|---|---|
| Age (year) | 1.02 | 1.01 - 1.03 | <0.001 |
| Smoking status | |||
| Non-smoker | 1.0 | ||
| Current smoker | 1.49 | 1.20 - 1.86 | <0.001 |
| Total cholesterol | 1.18 | 1.08 - 1.29 | <0.001 |
| HDL cholesterol | 0.41 | 0.29 - 0.58 | <0.001 |
| Qualifying event for ACS | |||
| Unstable angina | 1.0 | ||
| Single MI | 1.27 | 1.06 - 1.53 | 0.008 |
| Multiple MI | 1.92 | 1.55 - 2.39 | <0.001 |
| Revascularization | |||
| Never | 1.0 | ||
| Before ACS | 1.54 | 1.24 - 1.90 | <0.001 |
| Since ACS | 0.70 | 0.58 - 0.85 | <0.001 |
| History of stroke | |||
| No | 1.0 | ||
| Yes | 1.50 | 1.12 - 2.00 | 0.007 |
| Diabetes mellitus | |||
| No | 1.0 | ||
| Yes | 1.40 | 1.12 - 1.74 | 0.003 |
| Angina grade | |||
| CCVS < III | 1.0 | ||
| CCVS ≥ III | 1.44 | 1.16 - 1.80 | 0.001 |
| Treatment | |||
| Placebo | 1.0 | ||
| Pravastatin | 0.72 | 0.62 - 0.83 | <0.001 |
ACS = Acute Coronary Syndrome; CCVS = Canadian Cardiovascular Society Class of angina; HDL = High Density Lipoprotein; MI = Myocardial Infarction.