Figure 2.
Probability distribution of synaptic and dendritic currents. (A) The Purkinje cell model was stimulated with pairs of excitatory and inhibitory synaptic activity. The total excitatory synaptic current (IGlu) remained practically constant for all the combinations of excitatory and inhibitory activity (activity in Hz). (B) Probability distribution of the ICaP in response to the different combinations of excitatory and inhibitory activity in (A). (C) Probability distribution of IKc for the same simulations in (B). (D–F) The probability distribution of the other dendritic currents remained practically independent of level of synaptic activity. (G) The average firing rate at the soma remains constant for all combination of synaptic activity. (H) The Purkinje cell inter-spike distributions for each combination of synaptic activity in (A) have the same mean and standard deviation.