Skip to main content
. Author manuscript; available in PMC: 2010 Apr 19.
Published in final edited form as: J Neuropathol Exp Neurol. 2008 Oct;67(10):954–962. doi: 10.1097/NEN.0b013e3181875b2f

TABLE.

Summary of Transplantation Results

Age at Transplantation Weight, kg Cells Transplanted Graft Site Graft Detected Graft Size, mm GUSB Expression Time Point of Death
Dog 1 23 days 1.2 GUSB-OB-cNPC-MPIO* Left CN/Th Yes 1.1 Positive 8 days
Dog 2 23 days 1.3 GUSB-OB-cNPC-MPIO Left CN/Th Yes 0.54 Negative 4 weeks
Dog 3 23 days 1.4 GUSB-OB-cNPC Left CN/Th Yes 0.84 Positive 4 weeks
Dog 4 23 days 1.3 GUSB-OB-cNPC Left CN/Th No NA§ NA 4 weeks
Dog 5 5 months 8.5 OB-cNPC-MPIO|| Right cortex Yes NE NA 2 weeks
Dog 6 5 months 8.5 OB-cNPC-MPIO Right cortex Yes NE NA 2 weeks
Dog 7 5 months 7.8 OB-cNPC-MPIO Right cortex Yes NE NA 8 weeks
Dog 8 5 months 7.4 OB-cNPC-MPIO Right cortex Yes NE NA 8 weeks
*

GUSB-OB-cNPC-MPIO, canine olfactory-bulb NPCs transduced with β-glucuronidase vector and labeled with MPIO.

CN/Th, caudate nucleus/thalamus.

GUSB-OB-cNPC, canine olfactory-bulb NPCs transduced with β-glucuronidase vector.

§

NA, not applicable.

||

OB-cNPC-MPIO, canine olfactory-bulb NPCs labeled with MPIOs.

NE, not evaluated.