TABLE 3.
Coronary heart disease events by treatment assignment, baseline hot flush status, and year of study
| Estrogen + progestogen group (n = 1,387) |
Placebo group (n = 1,382) |
|||
|---|---|---|---|---|
| Study year | No significant hot flushes (n = 1,147) | Significant hot flushesa (n = 230) | No significant hot flushes (n = 1,178) | Significant hot flushesa (n = 204) |
| Year 1 | 47 | 10 | 37 | 1 |
| Year 2 | 36 | 11 | 40 | 9 |
| Year 3 | 31 | 4 | 33 | 9 |
| Year 4+ | 36 | 4 | 45 | 8 |
| Total | 150 | 29 | 155 | 27 |
Defined as hot flushes that were bothersome all, most, a good bit, or some of the time.