Table 2.
Results of Subjective Measures
| DRD4. L (n = 22) | OPRM1.G (n = 11) | Controls (n = 31) | ||||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | |
| Total AUDIT score | 12.80 | 4.95 | 12.11 | 4.70 | 11.10 | 4.90 |
| Baseline AUQ | 18.30 | 17.20 | 15.90 | 8.97 | 14.60 | 7.06 |
| Postscan AUQ | 19.70 | 5.84 | 15.30 | 8.33 | 17.60 | 7.65 |
| Postscan AUQ minus baseline AUQ | 2.19 | 5.62 | −0.36 | 10.90 | 2.72 | 5.00 |
| In-scanner alcohol urge rating (before priming) | 1.60 | 0.51 | 1.50 | 0.63 | 1.63 | 0.66 |
| In-scanner litchi urge rating (before priming) | 1.40 | 0.53 | 1.57 | 0.90 | 1.46 | 0.52 |
| In-scanner alcohol craving (after priming) | 2.02 | 0.79 | 1.54 | 0.63 | 1.97 | 6.81 |
| In-scanner litchi craving (after priming) | 1.91 | 0.64 | 1.51 | 0.743 | 1.81 | 0.65 |
| Post- minus prepriming in-scanner litchi urge rating | 0.53 | 0.58 | −0.06* | 0.53 | 0.33 | 0.39 |
| Post- minus prepriming in-scanner alcohol urge rating | 0.42 | 0.71 | 0.04 | 0.59 | 0.29 | 0.39 |
Mean values and standard deviations of subjective measures for each group are summarized in this table. T-tests revealed a significant difference between OPRM1.G individuals and controls (individuals with DRD4.S and OPRM1.A genotype) in the difference score between postscan minus prescan in scanner litchi urge ratings (p < 0.05). The groups did not differ in any of the other subjective measures.
t = −2.457, p = 0.02.