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Comparative biological evaluation of selected Amaryllidaceae constituents used in the study by Jimenez et al.
| HeLa cell growth inhibition |
protein synthesis inhibition |
DNA synthesis inhibition |
RNA synthesis inhibition |
|
|---|---|---|---|---|
| compound | MIC µM | IC50 µM | IC50 µM | IC50 µM |
| 44 | 0.1 | 0.07 | ~ 1 | > 1 |
| 39 | 100 | 300 | ~ 1000 | > 1000 |
| 3 | 6 | 4 | 20 | > 20 |
| 7 | 1 | 3 | > 100 | > 100 |
| 5 | 4 | 1 | ~ 10 | > 10 |
| 38 | 25 | 8 | 30 | > 100 |
