Figure 2. ICI 182780 but not MPP inhibits anchorage independent growth of GH3 cells.
GH3 cells were cultured on soft agar in complete medium containing ICI (10 nM) or (MPP 10 nM) as described in the materials and methods. A] Bright field microscopy shows GH3 cell colonies in soft agar. B] Quantitative analysis of GH3 cell colonies in soft agar following anti-estrogen treatment. Colonies were counted in at least 3 independent fields. Data is calculated as % of control and it is the mean ± SEM of 4 separate experiments. * indicates significant differences from control (p<0.05).
