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. Author manuscript; available in PMC: 2010 Apr 19.
Published in final edited form as: J Immunol. 2009 Sep 28;183(8):5121–5128. doi: 10.4049/jimmunol.0900811

FIGURE 6.

FIGURE 6

The chaperone function of gp96/gp93 is not dependent on intermolecular disulfide bond formation at the N terminus. A, Both WT gp96 and the gp96C138A mutant rescue the expression of the indicated gp96 clients. One representative result from multiple experiments is shown. B, Restoration of cell surface expression of gp96 clients by gp93 and gp93A137C. Cells with the same intensity for GFP were gated on and analyzed for cell surface expression of the indicated gp96 clients (white histogram). Gray histograms, background stain with isotype control Ab. At least two experiments were performed with similar results.