Table 2. Risk of renal cell carcinoma and exposure to occupational sunlight.
| Among all Participants | Among Male Participants | Among Female Participants | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | |||||||||||||||||||
| Sunlight | N | % | N | % | OR | 95% CI | p-trend | Sunlight | N | % | N | % | OR | 95% CI | p-trend | Sunlight | N | % | N | % | OR | 95% CI | p-trend | *LRT |
| Cumulative Exposure (low exposure-unit-yrs) | Cumulative Exposure (low exposure-unit-yrs) | Cumulative Exposure (low exposure-unit-yrs) | ||||||||||||||||||||||
| ≤5.25 | 352 | 33.3 | 476 | 33.2 | 1.00 | ≤6.00 | 197 | 31.5 | 269 | 29.0 | 1.00 | ≤4.50 | 134 | 31.0 | 187 | 37.0 | 1.00 | |||||||
| >5.25-9.55 | 363 | 34.3 | 476 | 33.2 | 1.05 | (0.85-1.31) | >6.00-16.10 | 235 | 37.6 | 352 | 38.0 | 0.83 | (0.64-1.08) | >4.50-5.80 | 135 | 31.3 | 149 | 29.5 | 1.17 | (0.83-1.65) | ||||
| >9.55 | 342 | 32.4 | 480 | 33.5 | 1.01 | (0.81-1.26) | 0.96 | >16.10 | 193 | 30.9 | 306 | 33.0 | 0.76 | (0.58-1.00) | 0.05 | >5.80 | 163 | 37.7 | 169 | 33.5 | 1.22 | (0.87-1.70) | 0.26 | 0.11 |
| Frequency-Adjusted Duration of Exposure (yrs) | Frequency-Adjusted Duration of Exposure (yrs) | Frequency-Adjusted Duration of Exposure (yrs) | ||||||||||||||||||||||
| ≤5.25 | 354 | 33.5 | 484 | 33.8 | 1.00 | ≤6.30 | 217 | 34.7 | 303 | 32.7 | 1.00 | ≤4.50 | 135 | 31.3 | 189 | 37.4 | 1.00 | |||||||
| >5.25-9.30 | 375 | 35.5 | 472 | 33.0 | 1.11 | (0.90-1.37) | >6.30-13.50 | 211 | 33.8 | 298 | 32.1 | 0.92 | (0.71-1.20) | >4.50-5.70 | 130 | 30.1 | 141 | 27.9 | 1.18 | (0.84-1.66) | ||||
| >9.30 | 328 | 31.0 | 476 | 33.2 | 1.00 | (0.80-1.25) | 0.96 | >13.50 | 197 | 31.5 | 326 | 35.2 | 0.76 | (0.58-0.99) | 0.04 | >5.70 | 167 | 38.7 | 175 | 34.7 | 1.22 | (0.88-1.71) | 0.24 | 0.14 |
| Frequency-Adjusted Duration of Exposure for Subjects with Only Low Intensity Jobs (yrs) | Frequency-Adjusted Duration of Exposure for Subjects with Only Low Intensity Jobs (yrs) | Frequency-Adjusted Duration of Exposure for Subjects with Only Low Intensity Jobs (yrs) | ||||||||||||||||||||||
| ≤5.25 | 350 | 40.6 | 474 | 39.4 | 1.00 | ≤6.30 | 216 | 44.4 | 294 | 39.1 | 1.00 | ≤4.50 | 132 | 35.2 | 185 | 40.9 | 1.00 | |||||||
| >5.25-9.30 | 347 | 40.3 | 440 | 36.5 | 1.09 | (0.87-1.36) | >6.30-13.50 | 175 | 35.9 | 263 | 35.0 | 0.84 | (0.64-1.11) | >4.50-5.70 | 127 | 33.9 | 138 | 30.5 | 1.21 | (0.85-1.71) | ||||
| >9.30 | 165 | 19.1 | 290 | 24.1 | 0.84 | (0.64-1.09) | 0.27 | >13.50 | 96 | 19.7 | 195 | 25.9 | 0.62 | (0.45-0.85) | 0.003 | >5.70 | 116 | 30.9 | 129 | 28.5 | 1.16 | (0.81-1.67) | 0.41 | 0.19 |
| Frequency-Adjusted Duration of Exposure for Subject with Any High Intensity Jobs (yrs) | Frequency-Adjusted Duration of Exposure for Subject with Any High Intensity Jobs (yrs) | Frequency-Adjusted Duration of Exposure for Subject with Any High Intensity Jobs (yrs) | ||||||||||||||||||||||
| ≤9.30 | 32 | 16.4 | 42 | 18.4 | 1.00 | ≤13.50 | 37 | 26.8 | 44 | 25.1 | 1.00 | ≤5.70 | 6 | 10.5 | 7 | 13.2 | 1.00 | |||||||
| >9.30 | 163 | 83.6 | 186 | 81.6 | 1.36 | (0.76-2.42) | 0.30 | >13.50 | 101 | 73.2 | 131 | 74.9 | 0.86 | (0.48-1.52) | 0.60 | >5.70 | 51 | 89.5 | 46 | 86.8 | 1.08 | (0.24-4.80) | 0.92 | 0.06 |
All values adjusted for age (continuous), sex, center, smoking status (ever, never), body mass index, and self-reported hypertension (no, yes)
Frequeny-adjusted duration of exposure for subjects with only high intensity jobs (yrs) not shown due to small numbers (Cases N= 39, Controls N= 31)
Tertile values based on exposure levels among all controls, all male controls, and all female controls
Likelihood Ratio Test
Years of exposure: all (range= 0.2-76.9yrs, mean= 10.1yrs, median= 6.4yrs); males (range= 0.2-76.9yrs, mean= 12.2yrs, median= 7.8yrs); females (range= 0.2-44.2yrs, mean= 6.7yrs, median= 5.3yrs)
Years of exposure for only low intensity jobs: all (range= 0.2-41.8yrs, mean= 8.1yrs, median= 5.9yrs); males (range= 0.2-41.8yrs, mean= 10.0yrs, median= 6.9yrs); females (range= 0.2-30.8yrs, mean= 5.4yrs, median= 5.0yrs)
Years of exposure for any high intensity jobs: all (range= 0.9-76.9yrs, mean= 19.7yrs, median= 18.7yrs); males (range= 3.5-76.9yrs, mean= 20.9yrs, median= 13.4yrs); females (range= 0.9-44.2yrs, mean= 16.54yrs, median= 13.9yrs)