Table 2.
Odds ratios for the association between lens opacities, cataract surgery and type of age-related macular degeneration (AMD) lesions in participants in the Los Angeles Latino Eye Study
| Soft Indistinct Drusen | Increased Retinal Pigment | RPE** Depigmentation | Any Advanced AMD | Geographic Atrophy | Exudative AMD | |
|---|---|---|---|---|---|---|
| Characteristic | OR (95%CI)* | OR (95%CI)* | OR (95%CI)* | OR (95%CI)* | OR (95%CI)* | OR (95%CI)* |
| Cataract | ||||||
| Absent | 1 | 1 | 1 | 1 | 1 | 1 |
| Present | 1.2(1.0, 1.5) | 0.8 (0.5, 1.0) | 0.8 (0.5, 1.4) | 0.5 (0.2, 1.1) | 0.8 (0.2, 3.5) | 0.7 (0.2, 1.7) |
| Nuclear sclerosis | ||||||
| Absent | 1 | 1 | 1 | 1 | 1 | 1 |
| Present | 1.2 (0.95, 1.6) | 1.0 (0.6, 1.3) | 1.3 (0.7, 2.4) | 1.9 (0.7, 4.9) | 2.2 (0.5, 10.2) | 1.7 (0.6, 4.5) |
| Posterior subcapsular | ||||||
| Absent | 1 | 1 | 1 | 1 | 1 | 1 |
| Present | 0.9 (0.6, 1.5) | 1.1 (0.5, 2.5) | 0.3 (0.0, 2.2) | 1.5 (0.5, 4.7) | 0.3 (0.0, 3.8) | 2.7 (0.8, 9.4) |
| Cortical | ||||||
| Absent | 1 | 1 | 1 | 1 | 1 | 1 |
| Present | 1.1(0.9, 1.4) | 0.9 (0.6, 1.3) | 0.9 (0.5, 1.7) | 0.5 (0.2, 1.6) | 0.2 (0.0, 1.8) | 0.9 (0.3, 2.6) |
| Mixed | ||||||
| Absent | 1 | 1 | 1 | 1 | 1 | 1 |
| Present | 1.0 (0.8, 1.5) | 1.4 (0.9, 2.3) | 1.5 (0.7, 3.3) | 1.3 (0.4, 4.6) | 0.3 (0.0, 4.3) | 2.8 (0.92, 8.5) |
| Cataract surgery | ||||||
| None | 1 | 1 | 1 | 1 | 1 | 1 |
| Yes | 1.0 (0.7, 1.4) | 1.6 (1.0, 2.6) | 2.2 (1.1, 4.4) | 2.8 (1.0, 7.8) | 2.6 (0.4, 14.7) | 2.8 (0.8, 9.6) |
*
Odds ratios adjusted for age, sex and smoking. Odds ratios in bold are statistically significant.
**
Retinal Pigment Epithelium