Table 2.
Association analysis of the 36 Dysbindin SNPs
| Marker rs # | position (bp) | alleles | MAF Cases | MAF Controlls | MAF Indices | MAF Parents | p | p (FH)* |
|---|---|---|---|---|---|---|---|---|
| rs9396591 | 15624264 | A/G | 0.24 (A) | 0.25 (A) | 0.27 (A) | 0.25 (A) | 0.8415 | 0.4755 |
| rs909626 | 15625663 | A/G | 0.15 (A) | 0.14 (A) | 0.16 (A) | 0.12 (A) | 0.0721 | 0.7512 |
| rs3778651 | 15626511 | A/G | 0.07 (A) | 0.07 (A) | 0.07 (A) | 0.06 (A) | 0.7983 | 0.5392 |
| rs13195001 | 15627382 | C/T | 0.25 (T) | 0.26 (T) | 0.25 (T) | 0.29 (T) | 0.1474 | 0.1394 |
| rs13198512 | 15627864 | C/T | 0.49 (C) | 0.49 (C) | 0.49 (C) | 0.48 (C) | 0.9189 | 0.1154 |
| rs1047631 | 15631080 | A/G | 0.16 (G) | 0.15 (G) | 0.16 (G) | 0.17 (G) | 0.9389 | 0.3351 |
| rs17470454 | 15631427 | A/G | 0.06 (A) | 0.07 (A) | 0.05 (A) | 0.07 (A) | 0.2926 | 0.1682 |
| rs742106 | 15632459 | C/T | 0.37 (T) | 0.35 (T) | 0.35 (T) | 0.36 (T) | 0.39 | 0.5033 |
| rs2056943 | 15632542 | A/G | 0.04 (G) | 0.04 (G) | 0.03 (G) | 0.04 (G) | 1 | 1 |
| rs16876575 | 15633136 | C/T | 0.15 (T) | 0.14 (T) | 0.13 (T) | 0.14 (T) | 0.427 | 0.4015 |
| rs9296976 | 15633432 | A/G | 0.08 (G) | 0.09 (G) | 0.07 (G) | 0.09 (G) | 0.4492 | 0.4678 |
| rs6937379 | 15633976 | A/G | 0.24 (A) | 0.26 (A) | 0.24 (A) | 0.25 (A) | 0.2189 | 0.305 |
| rs4712253 | 15634396 | C/T | 0.44 (T) | 0.43 (T) | 0.41 (T) | 0.43 (T) | 0.5594 | 0.7935 |
| rs4236167 | 15641930 | C/T | 0.49 (T) | 0.47 (T) | 0.49 (C) | 0.47 (T) | 0.2539 | 0.4537 |
| rs9396592 | 15646989 | A/G | 0.36 (A) | 0.36 (A) | 0.38 (A) | 0.35 (A) | 0.5467 | 0.3468 |
| rs12527121 | 15654192 | C/T | 0.08 (T) | 0.07 (T) | 0.09 (T) | 0.07 (T) | 0.3644 | 0.5023 |
| rs12203173 | 15705548 | A/G | 0.14 (G) | 0.14 (G) | 0.12 (G) | 0.14 (G) | 0.7536 | 0.132 |
| rs7752070 | 15712898 | A/G | 0.08 (G) | 0.09 (G) | 0.07 (G) | 0.08 (G) | 0.4885 | 0.8357 |
| rs1011313 | 15741411 | A/G | 0.11 (A) | 0.11 (A) | 0.08 (A) | 0.09 (A) | 0.8857 | 0.5616 |
| rs7768128 | 15756679 | A/G | 0.25 (G) | 0.27 (G) | 0.23 (G) | 0.27 (G) | 0.2886 | 0.3592 |
| rs2619528 | 15757808 | A/G | 0.2 (A) | 0.2 (A) | 0.19 (A) | 0.2 (A) | 0.8384 | 0.6198 |
| rs2619522 | 15761628 | G/T | 0.2 (G) | 0.2 (G) | 0.19 (G) | 0.2 (G) | 0.8211 | 0.6722 |
| rs2743854 | 15763248 | C/T | 0.08 (T) | 0.08 (T) | 0.07 (T) | 0.08 (T) | 0.5838 | 0.7152 |
| rs2619519 | 15764181 | A/G | 0.08 (A) | 0.08 (A) | 0.07 (A) | 0.08 (A) | 0.614 | 0.823 |
| rs1018381 | 15765049 | C/T | 0.08 (T) | 0.08 (T) | 0.06 (T) | 0.08 (T) | 0.6036 | 0.7546 |
| rs1474605 | 15766191 | A/G | 0.2 (G) | 0.2 (G) | 0.2 (G) | 0.21 (G) | 0.971 | 0.5535 |
| rs12196958 | 15766584 | A/T | 0.01 (A) | 0.01 (A) | 0.01 (A) | 0.01 (A) | 1 | 1 |
| rs1997679 | 15766884 | C/T | 0.31 (T) | 0.33 (T) | 0.29 (T) | 0.32 (T) | 0.3344 | 0.7447 |
| rs13192791 | 15767518 | C/T | 0.24 (T) | 0.25 (T) | 0.23 (T) | 0.25 (T) | 0.3595 | 0.6981 |
| rs9476886 | 15769440 | C/T | 0.26 (T) | 0.27 (T) | 0.24 (T) | 0.26 (T) | 0.616 | 0.111 |
| rs2619536 | 15771826 | C/T | 0.07 (C) | 0.09 (C) | 0.08 (C) | 0.09 (C) | 0.1775 | 0.8787 |
| rs2619538 | 15773188 | A/T | 0.47 (A) | 0.44 (A) | 0.47 (A) | 0.43 (A) | 0.0933 | 0.2158 |
| rs742207 | 15776846 | C/T | 0.08 (T) | 0.1 (T) | 0.09 (T) | 0.09 (T) | 0.1494 | 0.8267 |
| rs760760 | 15782155 | A/G | 0.17 (G) | 0.16 (G) | 0.2 (G) | 0.16 (G) | 0.6703 | 0.6062 |
| rs7755766 | 15783620 | C/T | 0.15 (C) | 0.15 (C) | 0.17 (C) | 0.16 (C) | 0.728 | 0.8622 |
| rs17407828 | 15784456 | C/G | 0.32 (C) | 0.33 (C) | 0.28 (C) | 0.35 (C) | 0.1885 | 0.1083 |
*
Positive family history of schizophrenia