Table 5.
Th1/Th2 Polarization in Splenocytes from IL-4 KO Mice
Cellulose (pg/mg protein) |
Pectin (pg/mg protein) |
|
---|---|---|
IL-4 | N/D | N/D |
IL-5 | 30.1 ± 6.3 | 26.8 ± 9.0 |
IL-13 | 133 ± 28 | 118 ± 12 |
IFN-γ | 7.8 ± 3.3 | 4.5 ± 1.1 |
IL-12 | 1703 ± 466 | 891 ± 145 |
IL-2 | 22552 ± 4766 | 9212 ± 2067 * |
IL-4 KO mice were fed 10% pectin (pectin) or 5% cellulose (cellulose) for 6 wks. Cytokines were measured from Con A treated splenocytes. Results are expressed in pg/ml/protein, means ± SEM, n=4
p<0.05, main effect of diet.