Table 4.

Whole eye wavefront errors after LASIK (6 mm diameter pupil).

	Wavefront Error (Root Mean Square, µm)						Mean MDD between treatments (µm)
	Before LASIK n=7	1 month n=5	3 months n=5	6 months n=10	12 months n=12	36 months n=16
All High Order Aberrations
Bladeless	0.28 ± 0.06	0.57 ± 0.17	0.58 ± 0.10	0.45 ± 0.14	0.47 ± 0.12	0.43 ± 0.11	0.21
Microkeratome	0.29 ± 0.08	0.51 ± 0.11	0.58 ± 0.13	0.47 ± 0.16	0.45 ± 0.12	0.40 ± 0.12
Spherical
Bladeless	0.08 ± 0.06	0.11 ± 0.10	0.10 ± 0.07	0.10 ± 0.08	0.15 ± 0.08	0.16 ± 0.09	0.11
Microkeratome	0.07 ± 0.06	0.15 ± 0.07a	0.10 ± 0.07b	0.12 ± 0.08	0.13 ± 0.10	0.18 ± 0.10c
Coma
Bladeless	0.15 ± 0.08	0.40 ± 0.18	0.42 ± 0.16	0.33 ± 0.16	0.33 ± 0.14	0.29 ± 0.14	0.27
Microkeratome	0.18 ± 0.08	0.33 ± 0.10c	0.41 ± 0.14	0.33 ± 0.15	0.31 ± 0.13	0.23 ± 0.12
Trefoil
Bladeless	0.15 ± 0.07	0.26 ± 0.19	0.29 ± 0.07	0.16 ± 0.13	0.15 ± 0.11	0.17 ± 0.10	0.19
Microkeratome	0.13 ± 0.05	0.25 ± 0..22	0.29 ± 0.14	0.21 ± 0.13	0.18 ± 0.10	0.17 ± 0.08

Data are presented as mean ± standard deviation.

There were no differences between femtosecond laser (bladeless) and microkeratome treatments at any time; the mean minimum detectable difference (mean MDD) between treatments is indicated (α=0.05/6, β=0.20, paired analysis).

^ap=0.03,

^bp=0.01,

^cp=0.02,

^dp<0.01, versus preoperative; P-values were adjusted for 5 comparisons by using the Bonferroni technique.