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Amino-Nogo inhibits α5 integrin. A, Amino-Nogo inhibits CHO-K1 adhesion on fibronectin. Trypsinized CHO-K1 cells were plated on fibronectin (1 μg/ml)-coated dishes in the presence of 40 nm Fc or Ng-Fc. MnCl2 (1 mm) and 20 μg/ml indicated antibodies were added when indicated. B, The number of attached cells was expressed as percentage of Fc control on fibronectin without MnCl2 or antibodies added.
